2024年欧洲肿瘤内科学会(ESMO)年会将于9月13日~17日在西班牙巴塞罗那召开。目前,ESMO官网已公布报告标题及壁报标题,《肿瘤瞭望》特将肺癌部分的口头报告进行汇总,如有缺漏和错误,欢迎留言指正。
编者按:2024年欧洲肿瘤内科学会(ESMO)年会将于9月13日~17日在西班牙巴塞罗那召开。目前,ESMO官网已公布报告标题及壁报标题,《肿瘤瞭望》特将肺癌部分的口头报告进行汇总,如有缺漏和错误,欢迎留言指正。
主席论坛(Presidential Symposium)
摘要号:LBA8
英文标题:Precision Immuno-Oncology for advanced Non-small cell lung cancer(NSCLC)patients with PD-(L)1 inhibitors Resistance(PIONeeR):a phase Ib/IIa clinical trial targeting identified resistance pathways
中文标题:关于晚期非小细胞肺癌(NSCLC)患者对PD-(L)1抑制剂耐药的精准免疫肿瘤学:一项针对已识别耐药通路的Ib/IIa期临床试验(PIONeeR)
讲者:Pascale Tomasini
优选口头报告(Proffered Paper Session)
摘要号:LBA48
英文标题:CCTG BR.31:A global,double-blind placebo-controlled,randomized phase III study of adjuvant durvalumab in completely resected non-small-cell lung cancer(NSCLC)
中文标题:CCTG BR.31:度伐利尤单抗辅助治疗完全切除NSCLC的全球、双盲、安慰剂对照、随机III期研究
讲者:Glenwood Goss
摘要号:LBA52
英文标题:Interim Analysis of GALAXIES Lung-201:Phase 2,Randomized,Open-label Platform Study of Belrestotug Plus Dostarlimab in Patients(pts)With Previously Untreated Locally Advanced/Metastatic(LA/M)PD-L1 High(TPS>/=50%)Non-Small Cell Lung Cancer(NSCLC)
中文标题:II期随机、开放标签平台研究GALAXIES Lung-201中期分析:Belrestotug联合Dostarlimab治疗初治局部晚期/转移性、PD-L1高表达(TPS≥50%)的NSCLC患者
讲者:David R Spigel
摘要号:LBA53
英文标题:Nivolumab(NIVO)plus relatlimab with platinum-doublet chemotherapy(PDCT)vs NIVO+PDCT as first-line(1L)treatment(tx)for stage IV or recurrent NSCLC:results from the randomized phase 2 RELATIVITY-104 study
中文标题:纳武利尤单抗+Relatlimab联合铂类双药化疗vs纳武利尤单抗+铂类双药化疗作为IV期或复发性NSCLC的一线治疗的随机II期RELATIVITY-104研究结果
讲者:Nicolas Girard
摘要号:LBA54
英文标题:Amivantamab Plus Chemotherapy vs Chemotherapy in EGFR-mutated,Advanced Non-small Cell Lung Cancer After Disease Progression on Osimertinib:2nd Interim Overall Survival From MARIPOSA-2
中文标题:埃万妥单抗联合化疗vs化疗用于奥希替尼治疗后疾病进展的EGFR突变晚期NSCLC:MARIPOSA-2试验第2次中期总生存(OS)分析
讲者:Sanjay Popat
摘要号:LBA55
英文标题:Mechanisms of Acquired Resistance to First-line Amivantamab Plus Lazertinib Versus Osimertinib in Patients With EGFR-mutant Advanced Non-Small Cell Lung Cancer:An Early Analysis from the Phase 3 MARIPOSA Study
中文标题:埃万妥单抗+拉泽替尼vs.奥希替尼一线治疗EGFR突变晚期非小细胞肺癌患者的获得性耐药机制:一项来自Ⅲ期MARIPOSA研究的早期分析
讲者:Benjamin Besse
摘要号:LBA81
英文标题:Durvalumab(D)as consolidation therapy in limited-stage SCLC(LS-SCLC):outcomes by prior concurrent chemoradiotherapy(cCRT)regimen and prophylactic cranial irradiation(PCI)use in the ADRIATIC trial
中文标题:度伐利尤单抗巩固治疗局限期小细胞肺癌(SCLC):ADRIATIC试验中根据既往接受的同步放化疗(cCRT)方案和预防性颅脑照射(PCI)使用状态分析的结果
讲者:Suresh Senan
摘要号:LBA83
英文标题:PECATI:A phase 2 trial to evaluate the efficacy and safety of lenvatinib in combination with pembrolizumab in pretreated advanced B3-thymoma and thymic carcinoma
中文标题:评估仑伐替尼联合帕博利珠单抗用于经治晚期B3胸腺瘤和胸腺癌的疗效和安全性的II期PECATI试验
讲者:Jordi Remon Masip
摘要号:608O
英文标题:Preliminary safety and clinical activity of ASP3082,a first-in-class,KRAS G12D selective protein degrader in adults with advanced pancreatic(PC),colorectal(CRC),and non-small cell lung cancer(NSCLC)
中文标题:首创KRAS G12D选择性蛋白降解剂ASP3082在晚期胰腺癌、结直肠癌和NSCLC成人患者中的初步安全性和临床活性
讲者:Wungki Park
摘要号:1253O
英文标题:Phase 1/2 ALKOVE-1 study of NVL-655 in ALK-positive(ALK+)solid tumors
中文标题:NVL-655治疗ALK阳性实体瘤的I/II期ALKOVE-1研究
讲者:Alexander E.Drilon
摘要号:1786O
英文标题:BMS-986012(anti-fucosyl-monosialoganglioside-1[fuc-GM1])with carboplatin+etoposide+nivolumab(CE/NIVO)as first-line(1L)therapy in extensive-stage small cell lung cancer(ES-SCLC):interim analysis(IA)of a randomized phase 2 study
中文标题:BMS-986012[抗岩藻糖基单唾液酸神经节苷脂-1(fuc-GM1)]联合卡铂+依托泊苷+纳武利尤单抗作为广泛期小细胞肺癌一线治疗:一项随机II期研究的中期分析
讲者:Ewa Kalinka
微型口头报告(Mini Oral Session)
摘要号:LBA49
英文标题:Associations of ctDNA clearance(CL)during neoadjuvant Tx with pathological response and event-free survival(EFS)in pts with resectable NSCLC(R-NSCLC):expanded analyses from AEGEAN
中文标题:可切除NSCLC患者新辅助治疗期间ctDNA清除率与病理缓解和无事件生存期(EFS)的关系:AEGEAN的扩展分析
讲者:Martin Reck
摘要号:LBA50
英文标题:Perioperative nivolumab(NIVO)v placebo(PBO)in patients(pts)with resectable NSCLC:clinical update from the phase 3 CheckMate 77T study
中文标题:对比纳武利尤单抗vs安慰剂用于可切除NSCLC患者的围手术期治疗:III期CheckMate 77T研究的临床更新
讲者:Jonathan D.Spicer
摘要号:LBA51
英文标题:Circulating tumor DNA(ctDNA)dynamics and treatment responses in chemotherapy-ineligible patients(pts)with unresectable Stage III NSCLC from the phase 2 DUART trial
中文标题:II期DUART试验中不适合化疗的无法切除III期NSCLC患者ctDNA动力学和治疗缓解
讲者:Andrea Riccardo Filippi
摘要号:LBA56
英文标题:Updated Efficacy and Safety From the Phase 2 PHAROS Study of Encorafenib Plus Binimetinib in Patients With BRAF V600E-Mutant Metastatic NSCLC(mNSCLC)
中文标题:恩考芬尼联合比美替尼治疗BRAF V600E突变转移性NSCLC患者的II期PHAROS研究的最新疗效和安全性
讲者:Gregory J.Riely
摘要号:LBA57
英文标题:Adagrasib(ADA)vs docetaxel(DOCE)in patients(pts)with KRASG12C-mutated advanced NSCLC and baseline brain metastases(BM):results from KRYSTAL-12
中文标题:对比Adagrasib vs多西他赛在患有KRAS G12C突变晚期NSCLC、基线脑转移的患者中的疗效:KRYSTAL-12的结果
讲者:Fabrice Barlesi
摘要号:1206MO
英文标题:ALINA:exploratory biomarker analyses in patients(pts)with resected ALK+non-small cell lung cancer(NSCLC)treated with adjuvant alectinib vs chemotherapy(chemo)
中文标题:ALINA试验中阿来替尼vs.化疗辅助治疗可切除ALK+非小细胞肺癌患者的探索性生物标志物分析
讲者:Ben J.Solomon
摘要号:1207MO
英文标题:Neoadjuvant nivolumab monotherapy for high-risk clinical stage I non-small cell lung cancer:A phase 2 POTENTIAL study
中文标题:纳武利尤单抗单药用于高危临床Ⅰ期非小细胞肺癌的新辅助治疗:一项Ⅱ期POTENTIAL研究
讲者:Yasuhiro Tsutani
摘要号:1208MO
英文标题:Phase III trial of perioperative pirfenidone therapy for lung cancer with idiopathic pulmonary fibrosis(IPF):NEJ034 study
中文标题:围手术期吡非尼酮用于发生特发性肺纤维化(IPF)的肺癌患者:Ⅲ期NEJ034研究
讲者:Yukinobu Goto
摘要号:1209MO
英文标题:Neoadjuvant nivolumab and nivolumab+ipilimumab in resectable non-small cell lung cancer:Combined analysis of 5-year outcomes from NEOSTAR and CA209-159
中文标题:纳武利尤单抗vs纳武利尤单抗+伊匹木单抗用于可切除NSCLC新辅助治疗:NEOSTAR和CA209-159试验5年结果综合分析
讲者:Joshua Reuss
摘要号:1240MO
英文标题:Quantitative radiomics for the detection of symptomatic pneumonitis following chemoradiotherapy in patients with Stage III unresectable NSCLC
中文标题:定量放射组学检测III期不可切除NSCLC患者放化疗后出现的症状性肺炎
讲者:Jarushka Naidoo
摘要号:1241MO
英文标题:Osimertinib(osi)after definitive chemoradiotherapy(CRT)in unresectable(UR)stg III EGFRm NSCLC:Analyses of CNS and distant progression from the Phase 3 LAURA study
中文标题:根治性放化疗后采用奥希替尼治疗不可切除Ⅲ期EGFR突变NSCLC:Ⅲ期LAURA试验中CNS和远处进展分析
讲者:陆舜教授丨上海交通大学附属胸科医院
摘要号:1242MO
英文标题:The addition of belomethason propionate inhalation to radical radiotherapy for patients with locally advanced non-small cell lung cancer:a randomized controlled,open-label phase II study
中文标题:局部晚期NSCLC患者在根治性放疗基础上加用丙酸倍氯米松吸入剂:一项随机对照、开放标签II期研究
讲者:张杰丨上海交通大学附属胸科医院
摘要号:1243MO
英文标题:A phase III study comparing weekly carboplatin plus nab-paclitaxel and daily low-dose carboplatin for concurrent chemoradiotherapy in elderly patients(≥75 years)with unresectable locally advanced NSCLC:JCOG1914
中文标题:比较每周卡铂联合白蛋白紫杉醇vs每日低剂量卡铂用于不可切除局部晚期NSCLC老年患者(≥75岁)的同步放化疗:Ⅲ期JCOG1914研究
讲者:Shota Omori
摘要号:1254MO
英文标题:Safety and Antitumor Activity of Zipalertinib in NSCLC Patients(pts)with EGFR Exon 20 Insertion(ex20ins)Mutations Who Received Prior Amivantamab
中文标题:Zipalertinib在既往接受过埃万妥单抗治疗的EGFR 20外显子插入突变NSCLC患者中的安全性和抗肿瘤活性
讲者:Antonio Passaro
摘要号:1255MO
英文标题:A Phase II Safety and Efficacy Study of PM8002/BNT-327 in Combination with Chemotherapy in Patients with EGFR-mutated Non-Small Cell Lung Cancer(NSCLC)
中文标题:PM8002/BNT-327联合化疗治疗EGFR突变NSCLC患者的安全性和疗效的Ⅱ期研究结果
讲者:吴一龙教授丨广东省人民医院
摘要号:1256MO
英文标题:Phase 1/2 ARROS-1 study of zidesamtinib(NVL-520)in ROS1 fusion-positive solid tumors
中文标题:评估Zidesamtinib(NVL-520)治疗ROS1融合阳性实体瘤的Ⅰ/Ⅱ期ARROS-1研究
讲者:Benjamin Besse
摘要号:1257MO
英文标题:ABBV-400,a c-Met Protein–Targeting Antibody-Drug Conjugate(ADC),in Patients(Pts)With Advanced EGFR Wildtype(WT)Non-Squamous(NSQ)Non-Small Cell Lung Cancer(NSCLC):Results From a Phase 1 Study
中文标题:靶向c-Met蛋白的抗体药物偶联物(ADC)ABBV-400治疗晚期EGFR野生型非鳞NSCLC的Ⅰ期研究的结果
讲者:María De Miguel
摘要号:1258MO
英文标题:Low dose versus standard dose pembrolizumab for treatment of stage 4 stage non-small cell lung carcinoma:Results of the pre-planned interim analysis of the NVALT-30 clinical trial
中文标题:低剂量vs.标准剂量帕博利珠单抗治疗Ⅳ期非小细胞肺癌:NVALT-30临床试验预先计划中期分析的结果
讲者:Michel Van den Heuvel
摘要号:1259MO
英文标题:Encorafenib plus binimetinib in patients(pts)with previously untreated BRAF V600E-mutant advanced Non-Small Cell Lung Cancer(NSCLC):an open-label,multicenter phase 2 trial(IFCT-1904 ENCO-BRAF)
中文标题:恩考芬尼联合比美替尼治疗初治BRAF V600E突变晚期NSCLC患者:开放标签、多中心Ⅱ期IFCT-1904 ENCO-BRAF试验
讲者:David Planchard
摘要号:1910MO
英文标题:ARTIMES:Automated Response evaluation to Treatment In MESothelioma
中文标题:ARTIMES:间皮瘤治疗疗效的自动评估
讲者:Kevin B.Groot Lipman